Viral-induced glomerular disease is a very important part of the spectrum of glomerulonephritis, especially since many...
Nephrology Viewpoints by Richard Glassock
CureGN-Diabetes Study
Observational, long-term cohort studies can play an important role for generating testable hypotheses to improve our....
Evaluation of Urine Protein Excretion in Lupus Nephritis
The “gold standard” for evaluation of urinary total protein excretion...
Therapy of Membranous Nephropathy in Advanced CKD
The treatment of membranous nephropathy (MN; PLA2R associated) has improved greatly in recent years, but uncertainties still exist concerning the treatment of such patients who have already advanced to stage 4...
Kidney Fibrosis Biomarkers in Type 2 Diabetes Treated with Dulaglutide
Kidney fibrosis is one of the final common end-points of progressive CKD in both diabetic and non-diabetic patients. But very few studies have attempted to evaluate kidney fibrosis and its progression...
Therapy of Hyperparathyroidism in CKD
The therapy of secondary hyperparathyroidism (SHPTH) in patients with advanced chronic kidney disease (CKD) presenting with 25-hydroxyvitamin D deficiency is not well established. Three approaches are ...
Prognostic Significance of Persistent Hematuria in IgA Nephropathy
Persistent high-grade hematuria is associated with an adverse impact on prognosis in IgA Nephropathy (IgAN), independent of proteinuria according to retrospective observational studies...
eGFR Calculations and Obesity
The definition of chronic kidney disease (CKD) using estimated glomerular filtration (eGFR) equations (indexed to a standard body surface area [BSA] of 1.73 m2) has been recognized as...
Calcium Deposition in Kidney Biopsy Specimens
Calcium deposition in the kidney parenchyma (using special stains such as the von Kossa stain), also known as dystrophic calcification, is a relatively common finding (about 10%) in native kidney biopsy specimens...
Serum Uromodulin Levels in IgA Nephropathy (IgAN): A Biomarker of Injury?
Uromodulin (UMOD or Tamm-Horsfall Protein) is synthesized and secreted by the thick ascending limb of the loop of Henle in the kidney. Mutations of the UMOD gene have been linked to...